International Standard
ISO/TS 4424:2023
Genomics informatics — Data elements and their metadata for describing the tumor mutation burden (TMB) information of clinical massive parallel DNA sequencing
Reference number
ISO/TS 4424:2023
Edition 1
International Standard
Read sample
ISO/TS 4424:2023
Published (Edition 1, 2023)

ISO/TS 4424:2023

ISO/TS 4424:2023
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This document identifies data elements and metadata to represent the information about tumor mutation burden (TMB) when reporting the value for the biomarker using clinical massive parallel DNA sequencing.

This document covers the TMB status and related metadata such as mutation type, sequencing types, and target areas of sequencing from human samples for clinical practice and research.

This document is not intended

     to define experimental protocols or methods for calculating the value of tumor mutation burden,

     for the other biological species, and

     for the Sanger sequencing methods.

General information

  •  : Published
     : 2023-12
    : International Standard published [60.60]
  •  : 1
     : 20
  • ISO/TC 215/SC 1
  • RSS updates

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This standard contributes to the following Sustainable Development Goal

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